Leila Rieder
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RESEARCH EXPERIENCE –––––––––––––––––––––––––––––––––––––––––––––––––––––––––
 
Postdoctoral Fellow     Brown University,  Molecular Biology, Cellular Biology, Biochemistry             2013-present
                                         Dr. Erica Larschan, PI
 
Associate Scientist I    Biogen Idec, Inc., Molecular Profiling Department                                                 2006-2008
         
 
EDUCATION –––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––
 
Ph.D              Brown University                                                                                                                          May 2013
                        Molecular Biology, Cellular Biology, Biochemistry
                        Dr. Robert Reenan, PI
 
M.A.               Brown University                                                                                                                                May 2011
                        Molecular Biology, Cellular Biology, Biochemistry
                        Dr. Robert Reenan, PI             
 
B.A.                Reed College                                                                                                                                         May 2006
                        Biology Department
                        Dr. Keith Karoly, advisor
 
 
RESEARCH INTERESTS ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––
 
I am interested in how the genes within the genome are regulated. More specifically, my research aims to understand how distinct pockets of the nucleus, called “nuclear bodies,” are sequestered for unique coordinated gene regulation. I use the model system Drosophila melanogaster because many elegant and established molecular and genetic tools exist in this organism. Using a variety of techniques including genetics, microscopy, biochemistry, and genomics, I have investigated the functions of specific proteins and genetic cues at two different nuclear bodies: the histone locus body and the male X chromosome. This research contributes to our understanding of nuclear biology and genetic regulation, which could lead to a better understanding of the pathologies of genetic diseases.
 
PUBLICATIONS –––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––
 
Rieder, LE, YA Savva, MA Reyna, YJ Chang, JS Dorsky, A Rezaei, RA Reenan (2015) Dynamic response of RNA editing to temperature in Drosophila. BMC Biology 13(1): 1. *Highly Accessed
 
Rieder, LE, EN Larschan. (2014) Wisdom from the fly. Trends in Genetics 30(11): 479-81.
 
Rieder, LE, CJ Staber, B Hoopengardener, RA Reenan (2013) Tertiary structural elements determine the extent and specificity of messenger RNA editing. Nature Communications 4: 2232.
 
Rieder, LE, RA Reenan (2012) The intricate relationship between RNA structure, editing, and splicing. Seminars in Cell and Developmental Biology 23(3):281-8.
 
Savva, YA*, LE Rieder*, RA Reenan. (2012) The ADAR protein family. Genome Biology 13(12):252-32. *Equal contributors
 
Allarie, NE, LE Rieder, J Bienkowska, JP Carulli (2008) Experimental comparison and cross-validation of Affymetrix HT plate and cartridge array gene expression platforms. Genomics 92(5):359-65. 
 
Rieder LE, AF Mensinger (2011) Strategies for increasing growth of juvenile toadfish. Biological Bulletin 201(2):283-5. 
 
MyBibliography: www.ncbi.nlm.nih.gov/myncbi/browse/collection/41281824/?sort=date&direction=descending
 
                       
GRANTS and FELLOWSHIPS––––––––––––––––––––––––––––––––––––––––––––––––––––––
 
Post-doctoral
            NIH Ruth Kirschstein NRSA F32 Fellowship (3rd percentile)                                                                              2014-2017 
Doctoral
            NSF Graduate Research Fellowship  Award                                                                                                              2009-2012
Undergraduate
            Howard Hughes Undergraduate Research Grants, Reed College                                                                         2005-2006
           
           
TEACHING EXPERIENCE ––––––––––––––––––––––––––––––––––––––––––––––––––––––––
 
Summer@Brown (high school), Brown University                                                                                           summer 2014, 2013
From Mad Cow Disease to Alzheimer’s: The Biological Basis of Disease
Organized and taught a two-week lecture/laboratory course for advanced high school students.
 
Invited guest lecturer (undergraduate), Brown University
                        BIOL1540/2540: Molecular Genetics                                                                                       March 2014, 2015, 2016
                        NEUR 1040: Introduction to Neurogenetics                                                                                                 March 2016
                                   
Teaching Assistant
                        Brown University (undergraduate)
                                    Genome Explorers                                                                                                                               summer, 2012                         
                                    Plant Organism                                                                                                                                             fall, 2010
                        Reed College (undergraduate)
                                    Introductory Chemistry Laboratory                                                                                                    2003-2006
 
Tutoring (undergraduate), Reed College
                        Science Center Tutor
                        Introductory, Organic Chemistry                                                                                                                      2004-2006
                        Individual Tutor
                        Introductory, Organic Chemistry                                                                                                                      2003-2006
 
 
MENTORING EXPERIENCE ––––––––––––––––––––––––––––––––––––––––––––––––––––––––
 
Larschan Lab (Brown University undergraduates)
           Talented undergraduates (names available upon request)                                                                                   2013-2015
 
Reenan Lab (Brown University undergraduates)
            Talented undergraduates (names available upon request)                                                                                  2010-2013
            
 
HONORS ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––
 
Poster Prizes:
Poster of the day, EMBO Conference (Birmingham, UK)                                                                                               Sept 2015
First prize, postdoc, Drosophila Research Conference (Chicago, IL)                                                                        March 2015
Brown MCB Department annual retreat (Providence, RI)                                                                                               Sept 2011
EMBO Workshop: chromatin structure, organization, dynamics (Prague, CZ)                                                          April 2011
 
Histochemical Society Travel Fellowship                                                                                                            March 2014
To attend the Marine Biological Laboratory Immunohistochemistry and microscopy course
 
Molecular Biosciences Training Grant, University of Wisconsin-Madison                                                   2008-2009
 
Commendation for Excellence in Scholarship, Reed College                                                                          2003-2006 
                       

ADDITIONAL RESEARCH EXPERIENCE ––––––––––––––––––––––––––––––––––––––––––––
 
Ph.D. Research            University of Wisconsin, Madison                                                                                2008-2009
                                        Cellular and Molecular Biology Department
                                        Dr. Michael Sussman, PI
 
Research Assistant      Marine Biological Laboratory (Woods Hole, MA)                                     summer, 2000-03, ‘05
                                         Dr. Allen Mensinger, PI
 
 
SERVICE and OUTREACH ––––––––––––––––––––––––––––––––––––––––––––––––––––––––
 
Brown University:
Brown University Fly Club founder and co-organizer:                                                                                              2013-present
Organize a monthly meeting that brings together Drosophila (and other fly) biologists from Brown and the surrounding area.                            
 
Molecular Biology, Cellular Biology and Biochemistry Data Club Postdoctoral Liaison:                                   2016-present
Organize talks within the department from graduate students, postdoctoral researchers, and faculty.
 
Brown SPARK and summer@brown programs:                                                                                           Summers, 2014-2016
Laboratory visits, hands-on laboratory demonstrations and guest lectures for middle and high school students.
 
Biogen, Inc:
Biogen community laboratory:                                                                                                                                           2006-2008
                        Assisted with laboratory activities for middle and high school students.                 
 
External Outreach:
Advisor to Columbia High School (alma mater) Science Olympiad Team                                                                 2014-2016
                        Advised high school students on specific events for New York and National competitions.
 
Publication Service:
Ad hoc reviewer: Proceedings of the National Academy of Sciences, PLoS Genetics [under mentorship]
 
 
PROFESSIONAL MEMBERSHIPS ––––––––––––––––––––––––––––––––––––––––––––––––––
 
American Society for Cell Biology                                                                                                                                 2016-present
National Postdoctoral Association                                                                                                                                2016-present
Genetics Society of America                                                                                                                                                2013-2015
RNA Society                                                                                                                                                                                      2012
American Association for the Advancement of Science                                                                                                  2011-2012
 
 
PROFESSIONAL DEVELOPMENT –––––––––––––––––––––––––––––––––––––––––––––––––
 
Teaching Advancement Courses and Workshops
            Yearlong courses at the Brown University Sheridan Center for Teaching and Learning:
                        Certificate I: Reflective Teaching                                                                                                                         2011
                        Certificate III: Professional Development                                                                                                         2014
                          
Research Courses and Workshops
            Immunohistochemistry and microscopy course, Marine Biological Laboratory                                                   2014
            Drosophila species workshop, Drosophila Research Conference, San Diego CA                                                  2014
  
 
RESEARCH COMMUNICATIONS ––––––––––––––––––––––––––––––––––––––––––––––––––
 
Invited presentations: International Conferences
European Molecular Biology Organization conference, Birmingham UK (speaker, poster)                                          2015
European Molecular Biology Organization conference, Nice FR (poster)                                                                          2012
European Molecular Biology Organization workshop on chromatin structure organization, and dynamics,
Prague CZ (session chair and poster)                                                                                                                                          2011
 
Invited presentations: National Conferences
American Society for Cellular Biology meeting (microsymposim speaker, poster)                                                            2016
Claremont-McKenna Keck Science Department Seminar Series (speaker)                                                                         2016
Rhode Island College Research Colloquium (speaker)                                                                                                             2016
4th Annual Northeast Regional Chromosome Pairing Conference (speaker)                                                                      2015
Drosophila Research Conference (poster)                                                                                                                                   2015
Drosophila Research Conference (poster)                                                                                                                                   2014
Gene Expression RNA Series (GEARS), Harvard Medical School (speaker)                                                                        2013
Gordon-Kenan Conference and Research seminar on RNA editing (poster)                                                                        2013
RNA Society annual meeting (speaker)                                                                                                                                         2012
Gordon-Kenan Conference and Research seminar on RNA editing (poster)                                                                         2011
 
Invited presentations: Internal
Molecular Biology, Cell Biology and Biochemistry department Data Club (speaker)                                                          2016
Brown University Fly Club (speaker)                                                                                                                                     2013-2016
Developmental Biology Research in Progress meeting (speaker)                                                                                              2014
 
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