RESEARCH EXPERIENCE –––––––––––––––––––––––––––––––––––––––––––––––––––––––––
Postdoctoral Fellow Brown University, Molecular Biology, Cellular Biology, Biochemistry 2013-present
Dr. Erica Larschan, PI
Associate Scientist I Biogen Idec, Inc., Molecular Profiling Department 2006-2008
EDUCATION –––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––
Ph.D Brown University May 2013
Molecular Biology, Cellular Biology, Biochemistry
Dr. Robert Reenan, PI
M.A. Brown University May 2011
Molecular Biology, Cellular Biology, Biochemistry
Dr. Robert Reenan, PI
B.A. Reed College May 2006
Biology Department
Dr. Keith Karoly, advisor
RESEARCH INTERESTS ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––
I am interested in how the genes within the genome are regulated. More specifically, my research aims to understand how distinct pockets of the nucleus, called “nuclear bodies,” are sequestered for unique coordinated gene regulation. I use the model system Drosophila melanogaster because many elegant and established molecular and genetic tools exist in this organism. Using a variety of techniques including genetics, microscopy, biochemistry, and genomics, I have investigated the functions of specific proteins and genetic cues at two different nuclear bodies: the histone locus body and the male X chromosome. This research contributes to our understanding of nuclear biology and genetic regulation, which could lead to a better understanding of the pathologies of genetic diseases.
PUBLICATIONS –––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––
Rieder, LE, YA Savva, MA Reyna, YJ Chang, JS Dorsky, A Rezaei, RA Reenan (2015) Dynamic response of RNA editing to temperature in Drosophila. BMC Biology 13(1): 1. *Highly Accessed
Rieder, LE, EN Larschan. (2014) Wisdom from the fly. Trends in Genetics 30(11): 479-81.
Rieder, LE, CJ Staber, B Hoopengardener, RA Reenan (2013) Tertiary structural elements determine the extent and specificity of messenger RNA editing. Nature Communications 4: 2232.
Rieder, LE, RA Reenan (2012) The intricate relationship between RNA structure, editing, and splicing. Seminars in Cell and Developmental Biology 23(3):281-8.
Savva, YA*, LE Rieder*, RA Reenan. (2012) The ADAR protein family. Genome Biology 13(12):252-32. *Equal contributors
Allarie, NE, LE Rieder, J Bienkowska, JP Carulli (2008) Experimental comparison and cross-validation of Affymetrix HT plate and cartridge array gene expression platforms. Genomics 92(5):359-65.
Rieder LE, AF Mensinger (2011) Strategies for increasing growth of juvenile toadfish. Biological Bulletin 201(2):283-5.
MyBibliography: www.ncbi.nlm.nih.gov/myncbi/browse/collection/41281824/?sort=date&direction=descending
GRANTS and FELLOWSHIPS––––––––––––––––––––––––––––––––––––––––––––––––––––––
Post-doctoral
NIH Ruth Kirschstein NRSA F32 Fellowship (3rd percentile) 2014-2017
Doctoral
NSF Graduate Research Fellowship Award 2009-2012
Undergraduate
Howard Hughes Undergraduate Research Grants, Reed College 2005-2006
TEACHING EXPERIENCE ––––––––––––––––––––––––––––––––––––––––––––––––––––––––
Summer@Brown (high school), Brown University summer 2014, 2013
From Mad Cow Disease to Alzheimer’s: The Biological Basis of Disease
Organized and taught a two-week lecture/laboratory course for advanced high school students.
Invited guest lecturer (undergraduate), Brown University
BIOL1540/2540: Molecular Genetics March 2014, 2015, 2016
NEUR 1040: Introduction to Neurogenetics March 2016
Teaching Assistant
Brown University (undergraduate)
Genome Explorers summer, 2012
Plant Organism fall, 2010
Reed College (undergraduate)
Introductory Chemistry Laboratory 2003-2006
Tutoring (undergraduate), Reed College
Science Center Tutor
Introductory, Organic Chemistry 2004-2006
Individual Tutor
Introductory, Organic Chemistry 2003-2006
MENTORING EXPERIENCE ––––––––––––––––––––––––––––––––––––––––––––––––––––––––
Larschan Lab (Brown University undergraduates)
Talented undergraduates (names available upon request) 2013-2015
Reenan Lab (Brown University undergraduates)
Talented undergraduates (names available upon request) 2010-2013
HONORS ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––
Poster Prizes:
Poster of the day, EMBO Conference (Birmingham, UK) Sept 2015
First prize, postdoc, Drosophila Research Conference (Chicago, IL) March 2015
Brown MCB Department annual retreat (Providence, RI) Sept 2011
EMBO Workshop: chromatin structure, organization, dynamics (Prague, CZ) April 2011
Histochemical Society Travel Fellowship March 2014
To attend the Marine Biological Laboratory Immunohistochemistry and microscopy course
Molecular Biosciences Training Grant, University of Wisconsin-Madison 2008-2009
Commendation for Excellence in Scholarship, Reed College 2003-2006
ADDITIONAL RESEARCH EXPERIENCE ––––––––––––––––––––––––––––––––––––––––––––
Ph.D. Research University of Wisconsin, Madison 2008-2009
Cellular and Molecular Biology Department
Dr. Michael Sussman, PI
Research Assistant Marine Biological Laboratory (Woods Hole, MA) summer, 2000-03, ‘05
Dr. Allen Mensinger, PI
SERVICE and OUTREACH ––––––––––––––––––––––––––––––––––––––––––––––––––––––––
Brown University:
Brown University Fly Club founder and co-organizer: 2013-present
Organize a monthly meeting that brings together Drosophila (and other fly) biologists from Brown and the surrounding area.
Molecular Biology, Cellular Biology and Biochemistry Data Club Postdoctoral Liaison: 2016-present
Organize talks within the department from graduate students, postdoctoral researchers, and faculty.
Brown SPARK and summer@brown programs: Summers, 2014-2016
Laboratory visits, hands-on laboratory demonstrations and guest lectures for middle and high school students.
Biogen, Inc:
Biogen community laboratory: 2006-2008
Assisted with laboratory activities for middle and high school students.
External Outreach:
Advisor to Columbia High School (alma mater) Science Olympiad Team 2014-2016
Advised high school students on specific events for New York and National competitions.
Publication Service:
Ad hoc reviewer: Proceedings of the National Academy of Sciences, PLoS Genetics [under mentorship]
PROFESSIONAL MEMBERSHIPS ––––––––––––––––––––––––––––––––––––––––––––––––––
American Society for Cell Biology 2016-present
National Postdoctoral Association 2016-present
Genetics Society of America 2013-2015
RNA Society 2012
American Association for the Advancement of Science 2011-2012
PROFESSIONAL DEVELOPMENT –––––––––––––––––––––––––––––––––––––––––––––––––
Teaching Advancement Courses and Workshops
Yearlong courses at the Brown University Sheridan Center for Teaching and Learning:
Certificate I: Reflective Teaching 2011
Certificate III: Professional Development 2014
Research Courses and Workshops
Immunohistochemistry and microscopy course, Marine Biological Laboratory 2014
Drosophila species workshop, Drosophila Research Conference, San Diego CA 2014
RESEARCH COMMUNICATIONS ––––––––––––––––––––––––––––––––––––––––––––––––––
Invited presentations: International Conferences
European Molecular Biology Organization conference, Birmingham UK (speaker, poster) 2015
European Molecular Biology Organization conference, Nice FR (poster) 2012
European Molecular Biology Organization workshop on chromatin structure organization, and dynamics,
Prague CZ (session chair and poster) 2011
Invited presentations: National Conferences
American Society for Cellular Biology meeting (microsymposim speaker, poster) 2016
Claremont-McKenna Keck Science Department Seminar Series (speaker) 2016
Rhode Island College Research Colloquium (speaker) 2016
4th Annual Northeast Regional Chromosome Pairing Conference (speaker) 2015
Drosophila Research Conference (poster) 2015
Drosophila Research Conference (poster) 2014
Gene Expression RNA Series (GEARS), Harvard Medical School (speaker) 2013
Gordon-Kenan Conference and Research seminar on RNA editing (poster) 2013
RNA Society annual meeting (speaker) 2012
Gordon-Kenan Conference and Research seminar on RNA editing (poster) 2011
Invited presentations: Internal
Molecular Biology, Cell Biology and Biochemistry department Data Club (speaker) 2016
Brown University Fly Club (speaker) 2013-2016
Developmental Biology Research in Progress meeting (speaker) 2014
Postdoctoral Fellow Brown University, Molecular Biology, Cellular Biology, Biochemistry 2013-present
Dr. Erica Larschan, PI
Associate Scientist I Biogen Idec, Inc., Molecular Profiling Department 2006-2008
EDUCATION –––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––
Ph.D Brown University May 2013
Molecular Biology, Cellular Biology, Biochemistry
Dr. Robert Reenan, PI
M.A. Brown University May 2011
Molecular Biology, Cellular Biology, Biochemistry
Dr. Robert Reenan, PI
B.A. Reed College May 2006
Biology Department
Dr. Keith Karoly, advisor
RESEARCH INTERESTS ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––
I am interested in how the genes within the genome are regulated. More specifically, my research aims to understand how distinct pockets of the nucleus, called “nuclear bodies,” are sequestered for unique coordinated gene regulation. I use the model system Drosophila melanogaster because many elegant and established molecular and genetic tools exist in this organism. Using a variety of techniques including genetics, microscopy, biochemistry, and genomics, I have investigated the functions of specific proteins and genetic cues at two different nuclear bodies: the histone locus body and the male X chromosome. This research contributes to our understanding of nuclear biology and genetic regulation, which could lead to a better understanding of the pathologies of genetic diseases.
PUBLICATIONS –––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––
Rieder, LE, YA Savva, MA Reyna, YJ Chang, JS Dorsky, A Rezaei, RA Reenan (2015) Dynamic response of RNA editing to temperature in Drosophila. BMC Biology 13(1): 1. *Highly Accessed
Rieder, LE, EN Larschan. (2014) Wisdom from the fly. Trends in Genetics 30(11): 479-81.
Rieder, LE, CJ Staber, B Hoopengardener, RA Reenan (2013) Tertiary structural elements determine the extent and specificity of messenger RNA editing. Nature Communications 4: 2232.
Rieder, LE, RA Reenan (2012) The intricate relationship between RNA structure, editing, and splicing. Seminars in Cell and Developmental Biology 23(3):281-8.
Savva, YA*, LE Rieder*, RA Reenan. (2012) The ADAR protein family. Genome Biology 13(12):252-32. *Equal contributors
Allarie, NE, LE Rieder, J Bienkowska, JP Carulli (2008) Experimental comparison and cross-validation of Affymetrix HT plate and cartridge array gene expression platforms. Genomics 92(5):359-65.
Rieder LE, AF Mensinger (2011) Strategies for increasing growth of juvenile toadfish. Biological Bulletin 201(2):283-5.
MyBibliography: www.ncbi.nlm.nih.gov/myncbi/browse/collection/41281824/?sort=date&direction=descending
GRANTS and FELLOWSHIPS––––––––––––––––––––––––––––––––––––––––––––––––––––––
Post-doctoral
NIH Ruth Kirschstein NRSA F32 Fellowship (3rd percentile) 2014-2017
Doctoral
NSF Graduate Research Fellowship Award 2009-2012
Undergraduate
Howard Hughes Undergraduate Research Grants, Reed College 2005-2006
TEACHING EXPERIENCE ––––––––––––––––––––––––––––––––––––––––––––––––––––––––
Summer@Brown (high school), Brown University summer 2014, 2013
From Mad Cow Disease to Alzheimer’s: The Biological Basis of Disease
Organized and taught a two-week lecture/laboratory course for advanced high school students.
Invited guest lecturer (undergraduate), Brown University
BIOL1540/2540: Molecular Genetics March 2014, 2015, 2016
NEUR 1040: Introduction to Neurogenetics March 2016
Teaching Assistant
Brown University (undergraduate)
Genome Explorers summer, 2012
Plant Organism fall, 2010
Reed College (undergraduate)
Introductory Chemistry Laboratory 2003-2006
Tutoring (undergraduate), Reed College
Science Center Tutor
Introductory, Organic Chemistry 2004-2006
Individual Tutor
Introductory, Organic Chemistry 2003-2006
MENTORING EXPERIENCE ––––––––––––––––––––––––––––––––––––––––––––––––––––––––
Larschan Lab (Brown University undergraduates)
Talented undergraduates (names available upon request) 2013-2015
Reenan Lab (Brown University undergraduates)
Talented undergraduates (names available upon request) 2010-2013
HONORS ––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––
Poster Prizes:
Poster of the day, EMBO Conference (Birmingham, UK) Sept 2015
First prize, postdoc, Drosophila Research Conference (Chicago, IL) March 2015
Brown MCB Department annual retreat (Providence, RI) Sept 2011
EMBO Workshop: chromatin structure, organization, dynamics (Prague, CZ) April 2011
Histochemical Society Travel Fellowship March 2014
To attend the Marine Biological Laboratory Immunohistochemistry and microscopy course
Molecular Biosciences Training Grant, University of Wisconsin-Madison 2008-2009
Commendation for Excellence in Scholarship, Reed College 2003-2006
ADDITIONAL RESEARCH EXPERIENCE ––––––––––––––––––––––––––––––––––––––––––––
Ph.D. Research University of Wisconsin, Madison 2008-2009
Cellular and Molecular Biology Department
Dr. Michael Sussman, PI
Research Assistant Marine Biological Laboratory (Woods Hole, MA) summer, 2000-03, ‘05
Dr. Allen Mensinger, PI
SERVICE and OUTREACH ––––––––––––––––––––––––––––––––––––––––––––––––––––––––
Brown University:
Brown University Fly Club founder and co-organizer: 2013-present
Organize a monthly meeting that brings together Drosophila (and other fly) biologists from Brown and the surrounding area.
Molecular Biology, Cellular Biology and Biochemistry Data Club Postdoctoral Liaison: 2016-present
Organize talks within the department from graduate students, postdoctoral researchers, and faculty.
Brown SPARK and summer@brown programs: Summers, 2014-2016
Laboratory visits, hands-on laboratory demonstrations and guest lectures for middle and high school students.
Biogen, Inc:
Biogen community laboratory: 2006-2008
Assisted with laboratory activities for middle and high school students.
External Outreach:
Advisor to Columbia High School (alma mater) Science Olympiad Team 2014-2016
Advised high school students on specific events for New York and National competitions.
Publication Service:
Ad hoc reviewer: Proceedings of the National Academy of Sciences, PLoS Genetics [under mentorship]
PROFESSIONAL MEMBERSHIPS ––––––––––––––––––––––––––––––––––––––––––––––––––
American Society for Cell Biology 2016-present
National Postdoctoral Association 2016-present
Genetics Society of America 2013-2015
RNA Society 2012
American Association for the Advancement of Science 2011-2012
PROFESSIONAL DEVELOPMENT –––––––––––––––––––––––––––––––––––––––––––––––––
Teaching Advancement Courses and Workshops
Yearlong courses at the Brown University Sheridan Center for Teaching and Learning:
Certificate I: Reflective Teaching 2011
Certificate III: Professional Development 2014
Research Courses and Workshops
Immunohistochemistry and microscopy course, Marine Biological Laboratory 2014
Drosophila species workshop, Drosophila Research Conference, San Diego CA 2014
RESEARCH COMMUNICATIONS ––––––––––––––––––––––––––––––––––––––––––––––––––
Invited presentations: International Conferences
European Molecular Biology Organization conference, Birmingham UK (speaker, poster) 2015
European Molecular Biology Organization conference, Nice FR (poster) 2012
European Molecular Biology Organization workshop on chromatin structure organization, and dynamics,
Prague CZ (session chair and poster) 2011
Invited presentations: National Conferences
American Society for Cellular Biology meeting (microsymposim speaker, poster) 2016
Claremont-McKenna Keck Science Department Seminar Series (speaker) 2016
Rhode Island College Research Colloquium (speaker) 2016
4th Annual Northeast Regional Chromosome Pairing Conference (speaker) 2015
Drosophila Research Conference (poster) 2015
Drosophila Research Conference (poster) 2014
Gene Expression RNA Series (GEARS), Harvard Medical School (speaker) 2013
Gordon-Kenan Conference and Research seminar on RNA editing (poster) 2013
RNA Society annual meeting (speaker) 2012
Gordon-Kenan Conference and Research seminar on RNA editing (poster) 2011
Invited presentations: Internal
Molecular Biology, Cell Biology and Biochemistry department Data Club (speaker) 2016
Brown University Fly Club (speaker) 2013-2016
Developmental Biology Research in Progress meeting (speaker) 2014
